PRP

REGENERATIVE MEDICINE

Facial rejuvenation with your own cells PRP

Regenerative Medicine is PRP and /or Autologous Cellular Rejuvenation

THE NEW ROLE IN BIOLOGICAL DERMAL REJUVENATION.

PRP Pioneering – PRP since 2003

A new approach, appealing to patients seeking a more natural method to facial rejuvenation, is regeneration with your own cells and more specifically, autologous PRP. This is also referred to as autologous cellular regeneration (ACR) an aesthetic practice.

PRP has been utilised in aesthetic medicine (UK, Japan, and Asia, Europe) to rejuvenate and help to slow down the aging process and face (2006). This refers to mesenchymal and epithelial rejuvenation by application of the persons own enriched autologous plasma. PRP was introduced into Australia 9 years ago, now with 112 published clinical papers to support its efficacy. PRP has been pioneered for facial rejuvenation in select patients with chronological aging. Regeneration or anti-aging by biological stimulation of resident stem cells by growth factors.

Science supports the use of PRP for the augmentation and regeneration of hard and soft tissues. PRP is the source of concentrated platelet content present in blood. Apart from assisting blood clotting, platelets also release growth factors that assist the human body to repair itself by stimulating cells to regenerate new tissue. Today,  can easily be separated from blood, through a process of centrifugation. Using your concentrated plasma permits the body to heal. Because your plasma transfusion is common practice in treating blood platelet disorders, including very low counts associated with bleeding.

Case studies reported in Europe, England, Asia, Japan and South Africa have demonstrated consistent rejuvenation of facial aging, including wrinkling in persons with modest grades of photo- or chronological aging. Patient selection is important and skin diseases have to be excluded. Improvement of skin texture and tone has been seen, these features are noticeable within 3 weeks with ongoing changes and improvement over the next few months, dependent on the health of the patient. Like all skin treatments the process can be enhanced by addition of appropriate Cosmeceuticals.

It is well known that platelets have many functions. Platelets contain important growth factors that, when secreted, are responsible for:

It is well known that platelets have many functions. Platelets contain important growth factors that, when secreted, are responsible for:

  • Tissue regeneration and rejuvenation
  • Increasing collagen production
  • Recruiting other cells to the site of injury
  • Initiating vascular in – growth
  • Inducing cell differentiation
  • Bone – mineralisation
  • Extra cellular matrix formation
  • Non – allergenic
  • It is a ‘body own’ physiological product vs. Animal derived or human donor products
  • Biological glue: for tissue adhesion, especially in skin flaps, bone grafts and trauma

These are vital steps in collagen regeneration and wound healing.

THE PROCESS IS

  1. Physiologically Active
  2. Preparation is Simple and Quick, and completed on the Physicians premises using the Regen approved PRP Harvesting system in the
  3. Can be used in multiple areas for dermal rejuvenation.

Prior to treatment a blood sample of 8ml – 32 ml is extracted from the patient. This blood is immediately placed in the centrifuge for 5 minutes in the approved RegenLab PRP harvesting tubes. When centrifugation is complete your Plasma will be separated into three layers: (1) platelet – poor plasma, (2) red blood cells, and (3) the ‘buffy coat’ ( i.e. platelets and white blood cells) from your red blood cells. The rich platelets are extracted from the base of the plasma gel. The platelets are injected into the mid to deep dermis of the skin. Platelets gradually increase collagen which can increase skin thickness and overall health of the skin.

HOW LONG IS THE PROCEDURE FROM START TO FINISH?

Approximately 45mins to 1 hour per two tubes.

WHICH FACIAL AND BODY AREAS CAN BE TREATED?
  • Around the eyes – Peri Orbital Rim
  • Cheeks and Mid face
  • Cheeks
  • Thinning skin on the neck
  • Jaw Line and Sub Malar
  • Back of hands
  • Decolletage
  • Other Body Areas knees, elbows, upper arms, post baby tummy
  • Combined with Lasers
  • Combined with skin needling
  • At the time of surgery
SIDE EFFECTS OF ACR- PRP FACIAL REJUVENATION
  • Minimal: Expect some swelling, bruising and redness for 12-24 hours. Some clients experience
  • Modest: Some patients may feel faint. A bruise at the venipuncture site may be visible for 2-3
  • EXCLUSION CRITERIA FOR RegenLab PRP FACIAL REJUVENATION

Persons with severe skin disease, cancer, chemotherapy, severe metabolic and systemic disorders, and abnormal platelet function (i.e. blood disorders). Anti­ coagulation therapy and underlying sepsis HIV, some auto immune disease excludes the use of PRP. Consultation is required to see if you are suited to a Regen ACR PRP Procedure.

EXPECTATIONS FOR RegenLab PRP
  • Hydration improvement is visible at 3 weeks and textural improvement is gradual over the next few months, dependent on the patient’s good health.
  • Cosmeceutical and Light therapies may enhance the
  • Advanced wrinkling cannot be reversed and a minimal improvement is predictable in persons with alcohol and tobacco
  • Severe scarring may not
  • Further PRP treatment is also popular and well tolerated, but patient selection is important if predictable results are to be
What do I need to do before a Regen PRP PROCEDURE?

If this treatment is suitable for you according to your healthcare professional:

  • Be well hydrated 48 hours leading up to the procedure
  • Reduce your Fat intake
  • Reduce your Alcohol and caffeine intake

Stop all Omegas, green teas and all supplements that increase bruising

Before treatment

Hair Image Before - Courtesy of Dr G Wong Sapphire Clinic NZ

After treatment

Before treatment

After treatment

REFERENCES: PLATELET RICH PLASMA

  • Redaelli, Romano, Marciano Face and Neck Revitalization with Platelet – Rich Plasma(PRP)Clinical outcome in a series of 23 Consecutively treated patients.
  • Cervelli VF Nicoli et al (2012) Treatment for traumatic scars using fat grafts mixed with platelet -rich plasma, and resurfacing of the skin Clin Exp Dermatol 37 (10 55-61)
  • ChoJM, et Effect of platelet -rich plasma on ultraviolet b induced skin wrinkles in nude mice, journal of plastic, reconstructive & aesthetic Surgery (2012), doi: 1016/j.bips.2010.08.014
  • Chajchir A Et Growth factors in Plastic Surgery. Aesth. Plast. Surg. 29: 295-299, 2005
  • Brown GL et al. Enhancement of wound healing by topical treatment with epidermal growth factor. N Engl J Med 321: 76-79, 1989
  • Eppley BL. Platelet quantification and growth factor analysis from platelet­ rich plasma: implications for wound healing. Plast Reconstruct Surg 114: 1502,2004
  • Eppley Platelet-rich plasma: A review of biology and applications in plastic surgery. Plast Reconstruct Surg 118: 147e, 2006
  • Bhanot S Et Current applications of platelet gels in facial plastic surgery. Facial Plast Surg 18, 27-33, 2002
  • Pietrzak WS et al. Platelet Rich Plasma: Biology and new technology. J Craniofacial Surgery, 16: 1043-1054, 2005
  • Presentation at Aesthetic Medicine Congress South Africa 5-6 October 2007 Gallagher Estate, Gaugteng (aestheticcongress.co.za ). Also, presented at the plastic surgery congress, Spier (ASSOCIATION OF PLASTIC AND RECONSTRUCTIVE SURGEONS OF SOUTHERN AFRICA: 21- 24 October 2007). Professor Donald du Toit. Aesthetic and biological facial rejuvenation treatment with REGENLAB Plasma (PRP). An alternative to photo-light resurfacing. Abstracts available.
  • DF du The Specialist Forum. State of the Art rejuvenation and normal wound healing with platelet-rich plasma growth factors. Part 1 and 2. 2007: 7; 36-42. Reprints available.
  • Review article on PRP. Shoulder surgeon and autologous cellular regeneration (ACR)-from bench to Part 1-the link between the human fibroblast, connective tissue disorders and shoulder. www.internationalshoulderjournal.org . 2007. D.F du Toit et al.
  • Soft and hard-tissue augmentation with platelet-rich plasma. Tissue culture dynamics, regeneration and molecular biology IJSS 2007;1:64-73. www.internationalshoulderjournal.org